Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo
نویسندگان
چکیده
منابع مشابه
Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo.
The perforant path (PP) undergoes synaptic changes in the course of aging and dementia. Previous studies attempting to assess the integrity of the PP in humans using diffusion tensor imaging (DTI) were limited by low resolution and the inability to identify PP fibers specifically. Here we present an application of DTI at ultrahigh submillimeter resolution that has allowed us to successfully ide...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2010
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1002113107